CANDID

Combined automated NOE assignment and structure determination module

CANDID is an algorithm for the automated assignment of NOESY spectra. Once nearly complete sequence-specific resonance assignments are available, the automated CANDID approach greatly enhances the efficiency of NOESY spectral analysis.

CANDID was written by Torsten Herrmann and Peter Güntert.

Availability

• A new, entirely probability-based automated NOESY assignment algorithm has replaced CANDID in CYANA from version 2.0 onwards. CANDID is part of the program CYANA 1.0.

• A different, stand-alone version of CANDID has been developed and is available from Torsten Herrmann.

References

• Herrmann, T., Güntert, P. & Wüthrich, K. Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA. J. Mol. Biol. 319, 209–227 (2002)